A new family of adenoviral vectors has been found to be better at delivering genetic cargo

Gene therapies can treat and potentially even cure some genetic diseases, but it’s difficult to get therapies to the parts of the body that need them. The researchers engineered viruses called adeno-associated viruses (AAVs) to carry cargo-; Like a working copy of the gene -; to specific cells and organs, but they do not always … Read more

Study reveals new rules for lineage evolution

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing diversity of neurons that regulate endocrine, autonomic, and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls the onset of puberty … Read more

Bioinformatic analysis of monkeypox virus host cell interactions

Although monkeypox virus infection is found predominantly in West and Central Africa, since May 2022 this double-stranded DNA virus has been reported in several countries outside Africa. Similar to the smallpox virus, monkeypox virus also belongs to the orthopoxvirus family and is less severe. The World Health Organization recently declared the global outbreak of monkeypox … Read more

Singapore researchers have identified a protein that transports degraded membrane lipids from lysosomes

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids from lysosomes, cellular organelles that are the cell’s breaking factories. The results are published in Proceedings of the National Academy of SciencesAnd the Increased understanding of the particle’s role in health and disease. “Particles are found in … Read more